Homology in anatomy ontologies: Report from a Phenotype RCN meeting

February 26, 2013

At the end of October 2012, the working groups of the Phenotype Research Coordination Network (RCN) all met at the Asilomar Conference Center, in Pacific Grove, CA. One of the groups, the Vertebrate working group, made it their goal to discuss methods of representing phylogenetic and serial homology in anatomy ontologies, an issue that is central to Phenoscape as well. Though common ancestry is implicit in the semantics of many classes and subclass relationships (see for example the ‘homology_notes’ for digit in Uberon), most multispecies anatomy ontologies, including¬†Uberon, VSAO, and TAO, do not assert homology relationships between anatomical entities. ¬†Nonetheless, homology is central to comparative biology, and therefore to enriching computations across data types, species, and evolutionary change.

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